Throughout the decade of 1880-1890, Walther Flemming, Eduard Strasburger, Edouard van Beneden, and others elucidate the essential facts of cell division and stressed the importance of the qualitative and quantitative equality of chromosome distribution to daughter cells.

Charles Darwin and his son Francis publish the results of their studies on plant responses to light, explaining that phototropism (bending toward the light) results from light reaching the top of a plant's shoot.

Pierre Curie discovers the piezoelectric effect: certain substances produce an electric current when they are physically distorted, and conversely they are physically distorted when an electric current is applied to them. This effect has many applications, including, in the 21st century, the construction of high-end tweeters in stereo systems.

James Albert Bonsack invents the first automated cigarette-rolling machine after seeing a tobacco company offer a prize for the first machine to roll and cut a cigarette. The Bonsack machine could roll up to 210 cigarettes per minute, compared to the average of four cigarettes per minute that could be rolled by hand. The Bonsack machine revolutionized the cigarette industry by making it possible to mass-produce inexpensive cigarettes.

Hermann Ludwig von Helmholtz shows that the electrical charges in atoms are divided into definite integral portions, suggesting the idea that there is a smallest unit of electricity.

Walther Flemming publishes accurate depictions of cell division (mitosis) in Zellsubstanz, Kern und Zelltheilung.

Eduard Strasburger coins the terms CYTOPLASM and NUCLEOPLASM.

W. Flemming discovers lampbrush chromosomes and coins the term MITOSIS.

Karl Alfred von Zittel describes an exceptionally well-preserved pterosaur wing showing flight membranes in detail.

Charles Darwin publishes his final letter to Nature, on the dispersal of freshwater bivalves. His obituary appears the same month. In this paper, Darwin acknowledges the assistance of W. D. Crick or Northampton. Later, Crick's grandson — Francis Crick — will be one of the co- discoverers of the structure of DNA.

John William Strutt, Lord Rayleigh, discovers that the ratio of the atomic mass of oxygen to that of hydrogen is not 16 exactly, as had been assumed, but 15.882.

The first hydro-electric plant opens, in Wisconsin.

August Weismann points out the distinction in animals between the somatic cell line and the germ cells, stressing that only changes in germ cells are transmitted to further generations.

Edouard van Beneden announced the principles of genetic continuity of chromosomes and reported the occurrence of chromosome reduction at germ cell formation. The sperm and egg are haploid and fertilization restores the diploid chromosome number.

Wilhelm Roux offers a possible explanation for the function of mitosis.

William Keith Brooks, a professor at The Johns Hopkins University, publishes The Law of Heredity: A Study of the Cause of Variation and the Origin of Living Organisms. Although this speculative work did not significantly advance the understanding of heredity, brooks' thinking is important because during his career he provided instruction to and supervised the early research of Thomas H. Morgan, Edmund Beecher Wilson, and William Bateson — ultimately some of the most important contributors to the new science of genetics.

Pierre Émile Duclaux introduces the custom of designating an enzyme by the by the name of the substrate on which its action was first reported and adding the suffix -ase.

Geologist James Hall names Cryptozoon, based on cabbagelike rocks up to meter across. Although Hall's biologic interpretation of these structures will be heavily criticized, it will ultimately prove correct.

Scheutz invents the first printing calculator

German engineer Gottlieb Daimler creates a portable engine that leads to the age of the automobile.

During 1884-88, identification of the cell nucleus as the basis for inheritance was independently reported by Oscar Hertwig, Eduard Strasburger, Albrecht von Kölliker, and August Weismann.

Gregor Mendel dies on January 6th, without ever knowing that his work on peas would lead to the transformation of biological research.

Walther Flemming, Eduard Strasburger and Edouard van Beneden demonstrate that chromosome doubling occurs by a process of longitudinal splitting. Strasburger describes and names the PROPHASE, METAPHASE, and ANAPHASEstages of chromosomal division.

George Eastman invents flexible, paper-based photographic film.

August Weismann formulates the germ-plasm theory which held that the germ plasm was separate from the somatoplasm and was continuous from generation to generation.

Carl Rabl theorized the individuality of chromosomes in all stages of the cell cycle.

Walther Flemming observed sister chromatids passing to opposite poles of the cell during mitosis.

Johann Jakob Balmer discovers the formula for the hydrogen spectrum that will later inspire Niels Bohr to develop his model of the atom.

James Dewar invents a thermos bottle in which heat is prevented from leaking via vacuum between two glass walls. The model becomes known as the Dewar Flask.

The world's first skyscraper, the Home Insurance Company Building, is erected in Chicago.

Francis Galton devised a new useful statistical tool, the correlation table.

Hugo de Vries (Holland) discovers aberrant evening primrose plants at Hilversum, Holland. Experiments with these extending over 15 years formed the basis for his mutation theory of evolution.

A. Ficatier publishes an account of the discovery of a trilobite perforated with two holes (perhaps to hang on a thread) at a Magdalenian- age site in France. The fossil lends the site its name of La Grotte du Trilobite.

John Bell Hatcher develops the "ant hill method of collecting minute fossils," collecting hundreds of tiny fossil teeth and jaws pushed to the surface by ants. He even carries shovelfuls of ants and sediment to other fossil localities in need of excavation by the arthropods.

William Crookes proposes that atomic weights measured by chemists are averages of the weights of different kinds of atoms of the same element (although it will not be until 1910 that Frederick Soddy identifies these different kinds of atoms as isotopes).

Worthington George Smith excavates a Bronze Age grave of a mother and child, surrounded by at least 200 fossil sea urchins, on Dunstable Downs. He nicknames the mother Maud.

August Weismann elaborated an all-encompassing theory of chromosome behavior during cell division and fertilization and predicted the occurrence of a reduction division (meiosis) in all sexual organisms.

Edouard van Beneden demonstrated chromosome reduction in gamete maturation, thereby confirming August Weismann's predictions.

Wilhelm Roux put forth the suggestion that the linearly arranged qualities of the chromosomes were equally transmitted to both daughter cells at meiosis.

Harry Govier Seeley determines that dinosaurs consist of "lizard- hipped" (saurischian) and "bird-hipped" (ornithischian) branches.

Albert Michelson and Edward Morley measure the velocity of light in two directions, attempting to detect the proper motion of Earth through the ether (a hypothesized fluid that was assumed to fill all space, providing a medium for the transport of electromagnetic waves). The Michelson Morley experiment reveals no evidence of motion.

Ernst Mach notes that airflow becomes disturbed at the speed of sound.

Dorr E. Felt was granted a patent for the Comptometer.

Introduction of the Comptometer by Felt & Tarrant Co

Celluloid film base introduced.

German anatomist W. von Waldeyer names chromosomes.

Heinrich Wilhelm Gottfried von Waldeyer names the CHROMOSOME.

Theodor Boveri verifies August Weismann's predictions of chromosome reduction by direct observation in Ascaris.

Heinrich Rudolf Hertz produces and detects radio waves for the first time. Radio waves will be called Hertzian waves until renamed by Marconi, who calls them radiotelegraphy waves.

Babbage's Analytical Engine Operates For The First Time

Burroughs Receives Patent for Calculating Machine

Introduction of its adder-lister by William Seward Burroughs

Eastman patents Kodak roll-film camera.

Louis Le Prince makes Roundhay Garden Scene. It is believed to be the first-ever motion picture on film.

John Boyd Dunlop, trained as a veterinary surgeon, devises the first practical pneumatic tire in response to a request from his son for a more comfortable tricycle. His first effort involved an inflated section of garden hose, fitted to the rear wheels of the tricycle. Although born in Scotland, Dunlop spent most of his life in Northern Ireland, where his image occurs on the current £10 note, issued by the Northern Bank.

Francis Galton publishes Natural Inheritance. In it he describes the quantitative measurement of metric traits in populations. He thus founds biometry and the statistical study of variation. Ultimately, he formulates the Law of Ancestral Inheritance, a statistical description of the relative contributions to heredity made by one's ancestors.

George Francis Fitzgerald formulates the principle that objects shrink slightly in the direction they are traveling, now known as the Fitzgerald-Lorenz contraction, since Hendrik Antoon Lorentz reaches the same conclusion a few years later.

Nintendo is founded as Nintendo Koppai on 23 September 1889 by craftsman Fusajiro Yamauchi in Shimogyo-ku, Kyoto, Japan, as an unincorporated establishment, to produce and distribute Japanese playing cards, or karuta (from Portuguese carta, 'card'), most notably hanafuda ('flower cards').

Herman Hollerith lodges patent for Punch Card technology

The first commercially available transparent celluloid roll film is introduced by the Eastman Company, later renamed the Eastman Kodak Company and commonly known as Kodak.