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Bibliography on: Classical Genetics: Mutation

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ESP: PubMed Auto Bibliography 08 Feb 2023 at 01:40 Created: 

Classical Genetics: Mutation

Wikipedia: We now know that, in biology, a mutation is the process that produces heritable change via the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA (such as may be caused by exposure to radiation or carcinogens), which then may undergo error-prone repair, or cause an error during other forms of repair, or else may cause an error during replication. Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. In the early days of classical genetics, work to characterize, model, and understand the phenomenology of mutation were critically important for developing the foundations of modern molecular genetics.

Created with PubMed® Query: 1859:1953[PDAT] AND (mutation OR mutant OR mutagen) NOT pmcbook NOT ispreviousversion

Citations The Papers (from PubMed®)

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RevDate: 2019-05-01
CmpDate: 2006-06-01

Labrum EL (1953)

The Effect of Generation Time on the Delayed Appearance of Induced Mutants in Escherichia Coli.

Proceedings of the National Academy of Sciences of the United States of America, 39(12):1221-1227.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Gowen JW, Stadler J, Plough HH, et al (1953)

Virulence and Immunizing Capacity of Salmonella Typhimurium as Related to Mutations in Metabolic Requirements.

Genetics, 38(6):531-549.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Fernandez B, Haas FL, O Wyss (1953)

Induced Host-Range Mutations in Bacteriophage.

Proceedings of the National Academy of Sciences of the United States of America, 39(10):1052-1057.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Doudney CO, RP Wagner (1953)

A Relationship of Homocysteine Metabolism to Thiamin, Serine, and Adenine Biosynthesis in a Mutant Strain of Neurospora.

Proceedings of the National Academy of Sciences of the United States of America, 39(10):1043-1052.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Levine RP, PT Ives (1953)

Mutation Rates and Lethal Gene Frequencies in Populations of Drosophila Melanogaster.

Proceedings of the National Academy of Sciences of the United States of America, 39(8):817-823.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Lefevre G, Ratty FJ, GD Hanks (1953)

Frequency of Notch Mutations Induced in Normal, Duplicated and Inverted X-Chromosomes of Drosophila Melanogaster.

Genetics, 38(4):345-359.

RevDate: 2021-09-16
CmpDate: 2007-02-02

House VL (1953)

The Interaction of Mutants Affecting Venation in Drosophila Melanogaster. II. Additive and Pattern Effects of Combinations of Hairless, Engrailed and Cubitus Interruptus.

Genetics, 38(4):309-327.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Weigle JJ (1953)

Induction of Mutations in a Bacterial Virus.

Proceedings of the National Academy of Sciences of the United States of America, 39(7):628-636.

RevDate: 2020-03-05
CmpDate: 2006-06-01

Young WJ, Yost HT, Ives PT, et al (1953)

The Effect of Pretreatment with Infra-Red Radiation on the X-ray Induced Sex-Linked Recessive Lethal and Visible Mutation Rate in Drosophila Melanogaster.

Proceedings of the National Academy of Sciences of the United States of America, 39(6):488-495.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Giles NH, CW Partridge (1953)

The Effect of a Suppressor on Allelic Inositolless Mutants in Neurospora Crossa.

Proceedings of the National Academy of Sciences of the United States of America, 39(6):479-488.

RevDate: 2021-09-15
CmpDate: 2007-02-02

Dunn LC, S Gluecksohn-Waelsch (1953)

Genetic Analysis of Seven Newly Discovered Mutant Alleles at Locus T in the House Mouse.

Genetics, 38(3):261-271.

RevDate: 2021-09-16
CmpDate: 2007-02-02

House VL (1953)

The Interaction of Mutants Affecting Venation in Drosophila Melanogaster. I. Interaction of Hairless, Engrailed and Cubitus Interruptus.

Genetics, 38(3):199-215.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Witkin EM (1953)

Effects of Temperature on Spontaneous and Induced Mutations in Escherichia Coli.

Proceedings of the National Academy of Sciences of the United States of America, 39(5):427-433.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Green MM (1953)

The Beadex Locus in Drosophila Melanogaster: On the Nature of the Mutants Bx and Bx.

Genetics, 38(1):91-105.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Hungate FP, TJ Mannell (1952)

Sulfur-35 as a Mutagenic Agent in Neurospora.

Genetics, 37(6):709-719.

RevDate: 2021-09-15
CmpDate: 2007-02-02

Dobzhansky T, Spassky B, N Spassky (1952)

A Comparative Study of Mutation Rates in Two Ecologically Diverse Species of Drosophila.

Genetics, 37(6):650-664.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Garber ED (1952)

"Bent-Tail," A Dominant, Sex-Linked Mutation in the Mouse.

Proceedings of the National Academy of Sciences of the United States of America, 38(10):876-879.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Altenburg LS, Altenburg E, RN Baker (1952)

Evidence Indicating That the Mutation Rate Induced in Drosophila by Low Doses of Ultraviolet Light Is an Exponential Function of the Dose.

Genetics, 37(5):558-561.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Altenburg LS, E Altenburg (1952)

The Lowering of the Mutagenic Effectiveness of Ultraviolet by Photoreactivating Light in Drosophila.

Genetics, 37(5):545-553.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Lederberg EM (1952)

Allelic Relationships and Reverse Mutation in Escherichia Coli.

Genetics, 37(5):469-483.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Maas WK, BD Davis (1952)

Production of an Altered Pantothenate-Synthesizing Enzyme by a Temperature-Sensitive Mutant of Escherichia Coli.

Proceedings of the National Academy of Sciences of the United States of America, 38(9):785-797.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Davis BD, WK Maas (1952)

Analysis of the Biochemical Mechanism of Drug Resistance in Certain Bacterial Mutants.

Proceedings of the National Academy of Sciences of the United States of America, 38(9):775-785.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Garber ED, Hackett AJ, R Franklin (1952)

The Virulence of Biochemical Mutants of Klebsiella Pneumoniae.

Proceedings of the National Academy of Sciences of the United States of America, 38(8):693-697.

RevDate: 2010-06-04
CmpDate: 2010-07-02

Garber ED (1952)

A Dominant, Sex-Linked Mutation in the House Mouse.

Science (New York, N.Y.), 116(3004):89.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Markert CL (1952)

Radiation-Induced Nutritional and Morphological Mutants of Glomerella.

Genetics, 37(4):339-352.

RevDate: 2018-12-01
CmpDate: 2010-07-02

McElroy WD (1952)

Evidence for the Occurrence of Intermediates during Mutation.

Science (New York, N.Y.), 115(2997):623-626.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Haddox CH (1952)

The Accumulation of alpha-Phenylglycine by Mutants of Neurospora Crassa Stimulated by Phenylalanine and Tyrosine.

Proceedings of the National Academy of Sciences of the United States of America, 38(6):482-489.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Haas F, Mitchell MB, Ames BN, et al (1952)

A Series of Histidineless Mutants of Neurospora Crassa.

Genetics, 37(3):217-226.

RevDate: 2021-10-20
CmpDate: 2006-05-31

Whitaker TW (1952)

Genetic and Chlorophyll Studies of a Yellow-Green Mutant in Muskmelon.

Plant physiology, 27(2):263-268.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Green MM (1952)

Mutant Isoalleles at the Vermilion Locus in Drosophila Melanogaster.

Proceedings of the National Academy of Sciences of the United States of America, 38(4):300-305.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Lein J, PS Lein (1952)

Studies on a Suppressor of Non-Allelic Acetate-Requiring Mutants of Neurospora.

Proceedings of the National Academy of Sciences of the United States of America, 38(1):44-48.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Bonner DM, Yanofsky C, CW Partridge (1952)

Incomplete Genetic Blocks in Biochemical Mutants of Neurospora.

Proceedings of the National Academy of Sciences of the United States of America, 38(1):25-34.

RevDate: 2018-12-02
CmpDate: 2014-02-18

DARKEN MA, NO SJOLANDER (1951)

Production of patulin by submerged fermentation.

Antibiotics & chemotherapy (Northfield, Ill.), 1(9):573-578.

RevDate: 2019-05-01
CmpDate: 2006-06-01

McDonald DJ (1951)

The Interaction of a Minute Mutation with a Sex-linked Lethal of Drosophila Melanogaster.

Proceedings of the National Academy of Sciences of the United States of America, 37(12):802-804.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Bryson V, H Davidson (1951)

Spontaneous and Ultra-Violet-Induced Mutations to Phage Resistance in Escherichia Coli.

Proceedings of the National Academy of Sciences of the United States of America, 37(12):784-791.

RevDate: 2018-12-02
CmpDate: 2014-02-18

WAISBREN BA, CARR C, D STRUXNESS (1951)

Role of inhibitors and mutations in antibiotic resistance by Escherichia coli.

Antibiotics & chemotherapy (Northfield, Ill.), 1(8):534-539.

RevDate: 2018-12-02
CmpDate: 2014-02-18

ROLAND F, CA STUART (1951)

Directed mutation toward streptomycin resistance in Salmonella typhi.

Antibiotics & chemotherapy (Northfield, Ill.), 1(8):523-529.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Moh CC, L Smith (1951)

An Analysis of Seedling Mutants (Spontaneous, Atomic Bomb-Radiation-, and X Ray-Induced) in Barley and Durum Wheat.

Genetics, 36(6):629-640.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Bertani G (1951)

A Method for Detection of Mutations, Using Streptomycin Dependence in Escherichia Coli.

Genetics, 36(6):598-611.

RevDate: 2021-09-15
CmpDate: 2007-02-02

Demerec M (1951)

Studies of the Streptomycin-Resistance System of Mutations in E. Coli.

Genetics, 36(6):585-597.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Hadorn E, HK Mitchell (1951)

Properties of Mutants of Drosophila Melanogaster and Changes During Development as Revealed by Paper Chromatography.

Proceedings of the National Academy of Sciences of the United States of America, 37(10):650-665.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Teas HJ, EG Anderson (1951)

Accumulation of Anthranilic Acid by a Mutant of Maize.

Proceedings of the National Academy of Sciences of the United States of America, 37(10):645-649.

RevDate: 2019-05-01
CmpDate: 2006-06-01

Plough HH, Miller HY, ME Berry (1951)

Alternative Amino Acid Requirements in Auxotrophic Mutants of Salmonella Typhimurium.

Proceedings of the National Academy of Sciences of the United States of America, 37(10):640-644.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Lieb M (1951)

Forward and Reverse Mutation in a Histidine-Requiring Strain of Escherichia Coli.

Genetics, 36(5):460-477.

RevDate: 2018-12-02
CmpDate: 2014-02-18

Anonymous (1951)

CHARLES Joseph Copp.

Bulletin of the Academy of Medicine, Toronto, 24(10):162.

RevDate: 2021-09-16
CmpDate: 2007-02-02

Soost RK (1951)

Comparative Cytology and Genetics of Asynaptic Mutants in Lycopersicon Esculentum Mill.

Genetics, 36(4):410-434.

RevDate: 2021-09-15
CmpDate: 2007-02-02

Herskowitz IH (1951)

The Genetic Basis of X-Ray Induced Recessive Lethal Mutations.

Genetics, 36(4):356-363.

RevDate: 2021-10-20
CmpDate: 2006-05-31

Teas HJ, AC Newton (1951)

TRYPTOPHAN, NIACIN, AND INDOLEACETIC ACID IN SEVERAL ENDOSPERM MUTANTS AND STANDARD LINES OF MAIZE.

Plant physiology, 26(3):494-501.

RevDate: 2018-12-02
CmpDate: 2014-02-18

SHOCKMAN G, SA WAKSMAN (1951)

Rhodomycin--an antibiotic produced by a red-pigmented mutant of Streptomyces griseus.

Antibiotics & chemotherapy (Northfield, Ill.), 1(1):68-75.

RevDate: 2021-10-21
CmpDate: 2014-02-18

FALCONER DS, FRASER AS, JW KING (1951)

The genetics and development of 'crinkled', a new mutant in the house mouse.

Journal of genetics, 50(2):324-344.

RevDate: 2021-10-21
CmpDate: 2014-02-18

WELLS DG (1951)

Inheritance and linkage relations of some foliage colour mutants in peas.

Journal of genetics, 50(2):215-220.

RevDate: 2018-12-02
CmpDate: 2014-02-18

MITTWOCH U (1951)

Studies in the genetics of some x-ray-induced morphological mutants in Coprinus lagopus.

Journal of genetics, 50(2):202-205.

RevDate: 2021-10-21
CmpDate: 2014-02-18

FALCONER DS (1951)

Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.).

Journal of genetics, 50(2):192-201.

RevDate: 2019-11-12
CmpDate: 2014-02-18

ROTHFELS KH (1950)

Chromosome complement, polyploidy and supernumeraries in Neopodismopsis abdominalis (Acrididae).

Journal of morphology, 87(2):287-315.

RevDate: 2018-12-01
CmpDate: 2004-09-30

MICKLER EE, LW DIGGS (1950)

The detection of the sickle cell trait; a comparison of the sealed moist preparation using capillary blood collected during venous stasis and the sodium bisulfite method.

American journal of clinical pathology, 20(9):861-864.

RevDate: 2019-06-18
CmpDate: 2004-09-30

BEATTY RA, M FISCHBERG (1950)

"Polyploidy in rabbits".

Nature, 166(4214):238-239.

RevDate: 2019-06-18
CmpDate: 2004-09-30

REGEHR H, ARNASON TJ, HE JOHNS (1950)

Induction of mutation by high-energy x-radiation produced by a 23-MeV. betatron.

Nature, 166(4214):228-229.

RevDate: 2019-05-01
CmpDate: 2004-09-30

DONALDSON JM (1950)

Inversion of the uterus.

British medical journal, 2(4674):331-332.

RevDate: 2019-06-16
CmpDate: 2004-09-30

PRICE PB (1950)

The meaning of bacteriostasis, bactericidal effect, and rate of disinfection.

Annals of the New York Academy of Sciences, 53(1):76-90.

RevDate: 2018-12-01
CmpDate: 2004-09-30

ADAMS MH (1950)

A heat resistant mutant of bacterial virus T5.

Bulletin of the New York Academy of Medicine, 26(8):566-568.

RevDate: 2019-06-18
CmpDate: 2004-09-30

LEWIN RA (1950)

Induced vitamin-requiring mutants of Chlamydomonas.

Nature, 166(4213):196.

RevDate: 2019-11-09
CmpDate: 2004-09-30

RULON O (1950)

The modification of developmental patterns in the sand dollar with sodium azide.

Physiological zoology, 23(3):236-247.

RevDate: 2019-06-18
CmpDate: 2004-09-30

SANSOME E (1950)

Reciprocal translocations in Pisum.

Nature, 166(4209):37-38.

RevDate: 2021-05-26
CmpDate: 2004-09-30

DAVIS BD, ES MINGIOLI (1950)

Mutants of Escherichia coli requiring methionine or vitamin B12.

Journal of bacteriology, 60(1):17-28.

RevDate: 2019-05-01
CmpDate: 2004-09-30

WHITING AR (1950)

Absence of mutagenic action of x-rayed cytoplasm in Habrobracon.

Proceedings of the National Academy of Sciences of the United States of America, 36(7):368-372.

RevDate: 2021-09-15
CmpDate: 2004-09-30

BURNHAM CR (1950)

Chromosome segregation in translocations involving chromosome 6 in maize.

Genetics, 35(4):446-481.

RevDate: 2019-11-08
CmpDate: 2004-09-30

ALLINGTON HV (1950)

Chapping of the skin on returning from the tropics to a cooler area.

Archives of dermatology and syphilology, 62(1):141-142.

RevDate: 2019-05-09
CmpDate: 2004-09-30

WOOD WB, MR SMITH (1950)

Host-parasite relationships in experimental pneumonia due to pneumococcus type III.

The Journal of experimental medicine, 92(1):85-100.

Experimental pneumonia was produced with a highly virulent strain of type III pneumococcus which synthesizes, during rapid growth, large amounts of capsular polysaccharide. The type III pneumonia differed from that caused by pneumococcus I in that (a) death occurred more promptly in the type III infection, (b) the local pulmonary lesion became more heavily infected, and (c) frank suppuration was common even after otherwise effective chemotherapy. The greater pathogenicity of the type III organism was shown by special histologic techniques to be due primarily to its capsular slime layer which interferes with surface phagocytosis. Capsular polysaccharide shed from the organism during growth was also demonstrated in high concentration in certain parts of the pneumonic lesion. Removal of the excess polysaccharide from the alveoli resulted from (a) lymphatic drainage to regional lymph nodes and (b) phagocytosis, particularly by macrophages. The possible relationship of the free carbohydrate to the malignancy and the characteristically viscous exudate of type III pneumonia was discussed. The lung abscesses which resulted from type III infection were observed to occur in those areas in which the maximum number of organisms had accumulated. Evidence was obtained that suppuration was due, not to necrotoxic products peculiar to the type III pneumococcus, but rather to the survival of large numbers of bacteria in the tissues, brought about primarily by the antiphagocytic effect of the slime layer. When pneumonia was produced with an intermediate type III mutant lacking the protective slime layer, back mutation to the mucoid parent occurred during the course of the infection, and the mucoid form eventually predominated in the lung as a result of selective phagocytosis of the intermediate organisms. Similar mutation to the maximally virulent type III form was noted with a transformed intermediate type III strain grown from single cell preparations.

RevDate: 2019-06-29
CmpDate: 2004-09-30

WOODWARD RB, G SINGH (1950)

The structure of patulin.

Experientia, 6(6):238-240.

RevDate: 2019-06-18
CmpDate: 2004-09-30

VAARAMA A (1950)

Accessory isochromosomes in the moss dicranum majus.

Nature, 165(4205):894.

RevDate: 2019-06-19
CmpDate: 2004-09-30

HIRATA Y, NAKANISHI K, H KIKKAWA (1950)

Xanthopterin obtained from the skins of the yellow mutant of Bombyx mori (silkworm).

Science (New York, N.Y.), 111(2892):608-609.

RevDate: 2018-12-02
CmpDate: 2014-02-18

ARMSTRONG JM (1950)

A tetraploid form of annual rape induced by colchicine.

Transactions of the Royal Society of Canada. Section 5, Biological sciences. Royal Society of Canada, 44(3):21-38.

RevDate: 2019-11-09
CmpDate: 2004-09-30

MULLER HJ (1950)

Partial dominance in relation to the need for studying induced mutations individually.

Journal of cellular physiology. Supplement, 35(Suppl. 1):205-210.

RevDate: 2019-11-09
CmpDate: 2004-09-30

PLOUGH HH (1950)

Radiation induced mutations in chemical requirements in Salmonella typhimurium.

Journal of cellular physiology. Supplement, 35(Suppl. 1):141-155.

RevDate: 2021-05-26
CmpDate: 2004-09-30

KLEIN HP, M DOUDOROFF (1950)

The mutation of Pseudomonas putrefaciens to glucose utilization and its enzymatic basis.

Journal of bacteriology, 59(6):739-750.

RevDate: 2019-08-23
CmpDate: 2004-09-30

BUGELSKI BR (1950)

A remote association explanation of the relative difficulty of learning nonsense syllables in a serial list.

Journal of experimental psychology, 40(3):336-348.

RevDate: 2019-10-26
CmpDate: 2004-09-30

BODINE JH (1950)

The action of sodium azide upon the oxygen uptake of mitotically active and blocked embryos.

Journal of cellular and comparative physiology, 35(3):461-479.

RevDate: 2018-12-01
CmpDate: 2004-09-30

JOHNSTON CF (1950)

Inversion of the uterus--report of a case.

Virginia medical monthly, 77(6):301-303.

RevDate: 2018-12-01
CmpDate: 2004-09-30

JAYNE M, BATSON HC, M BROWN (1950)

Preservation of albumin-fortified and unfortified blocking-type Rh antiserum with sodium azide.

The Journal of laboratory and clinical medicine, 35(6):988-992.

RevDate: 2019-05-09
CmpDate: 2004-09-30

COHEN SS, R ARBOGAST (1950)

Chemical studies in host-virus interactions; a comparison of some properties of three mutant pairs of bacterial viruses, T2r and T2r, T4r and T4r, T6r and T6r.

The Journal of experimental medicine, 91(6):619-636.

Various chemical and physiological aspects of the reproductive cycles of r(+) and r strains of T2, T4, and T6 viruses have been examined and compared. These include the ultraviolet absorption spectra in which differences between r and r(+) strains were not observed, though they were obtained in the case of T2, T4, and T6. Adsorption of T4 and T6 was found to require the adsorption cofactor l-tryptophane. Among the r and r(+) strains of these viruses limiting tryptophane requirements for adsorption were found to be different. Some differences were observed in the one-step growth curves of these viruses under conditions of single and multiple infection. The turbidity-time relations of infected cultures were characteristically different. The rates of DNA and protein synthesis in the infected cells were found to be independent of the viruses used. Certain implications of the data have been discussed.

RevDate: 2019-05-09
CmpDate: 2004-09-30

COHEN SS, R ARBOGAST (1950)

Chemical studies in host-virus interactions; immunochemical studies on the purity of concentrates of various bacterial viruses prepared by differential centrifugation procedures with an appendix summarizing data on the desoxyribonucleic acid content of these viruses.

The Journal of experimental medicine, 91(6):607-618.

Three mutant pairs of bacterial viruses T2r(+) and T2r, T4r(+) and T4r, T6r(+) and T6r, have been concentrated by differential centrifugation and analyzed. Under conditions of prolonged lysis of organisms grown on broth-agar, the virus concentrates frequently contained phosphorus (P) other than that contained in desoxyribose nucleic acid (DNA). These concentrates reacted with antisera to the host organism, E. coli, specifically precipitating the non-DNA-P but not virus activity or DNA. The amounts of nitrogen precipitated in the virus concentrates by antisera were related to their content of non-DNA-P. These viruses could be purified by differential centrifugation after such treatment to yield preparations apparently free of P other than DNA-P. It has been concluded that there is no satisfactory evidence for the presence of ribose nucleic acid as a constituent part of these viruses.

RevDate: 2018-12-01
CmpDate: 2004-09-30

GOOD IJ (1950)

On the inversion of circulant matrices.

Biometrika, 37(1-2):185-186.

RevDate: 2019-06-18
CmpDate: 2004-09-30

HAGGQVIST G, A BANE (1950)

Polyploidy in rabbits, induced by colchicine.

Nature, 165(4204):841-843.

RevDate: 2019-06-19
CmpDate: 2004-09-30

duBUY HG, WOODS MW, MD LACKEY (1950)

Enzymatic activities of isolated normal and mutant mitochondria and plastids of higher plants.

Science (New York, N.Y.), 111(2891):572-574.

RevDate: 2019-05-13
CmpDate: 2004-09-30

GARBER ED, FC HAUTH (1950)

A new mutation with asymmetrical expression in the mouse.

The Journal of heredity, 41(5):122-124.

RevDate: 2018-12-01
CmpDate: 2004-09-30

DIANZANI MU (1950)

[Mutations induced by bacterial nucleic acids].

Bollettino dell'Istituto sieroterapico milanese, 29(5-6):161-172.

RevDate: 2018-12-01
CmpDate: 2004-09-30

ALMANSA DE CARA S (1950)

[Synergic action of p-amino-salicylic acid and streptomycin in antituberculosis bacteriostasis].

Medicina, 18(5):350-355.

RevDate: 2018-12-01
CmpDate: 2004-09-30

PFANDLER U (1950)

[Some mutations affecting the eyes, collected as examples in the canton of Neuchatel and the Jura Bernois (congenital aniridia, universal albinism, congenital anophthalmos, total achromatopsia, oligophrenia associated with keratoconus, with ectopy of the crystalline, with congenital cataract and with atrophy of the optic nerve)].

Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 6(2):134-146.

RevDate: 2018-12-01
CmpDate: 2004-09-30

BUTTIAUX R KESTELOOT A (1950)

[In vivo mutations of Paracolobactrum].

Annales de l'Institut Pasteur, 78(5):691-694.

RevDate: 2018-12-01
CmpDate: 2004-09-30

SCALONE I (1950)

[Results of treatment with factor AF-2 in 656 cases of inoperable cancer of the breast].

Clinica y laboratorio, 49(290):338-356.

RevDate: 2021-09-15
CmpDate: 2004-09-30

RAUT C (1950)

Effect of concentration of pantothenate on selection of a mutant for pantothenate synthesis in Saccharomyces cerevisiae.

Genetics, 35(3):381-395.

RevDate: 2018-12-01
CmpDate: 2004-09-30

MARSHALL M, McNAMARA TM, JW SCHULTE (1950)

Fatal acute agranulocytosis following prolonged administration of small doses of sulfadiazine for urinary bacteriostasis.

California medicine, 72(5):390-391.

RevDate: 2018-12-01
CmpDate: 2004-09-30

POLLOCK JH (1950)

Hyperpigmentation improved by treatment with monobenzyl ether of hydroquinone.

Archives of dermatology and syphilology, 61(5):873-875.

RevDate: 2019-06-29
CmpDate: 2004-09-30

SOBELS FH (1950)

[Experimental breeding of offsprings of lethal ovaries of a mutant letal-translucida from Drosophila melanogaster].

Experientia, 6(4):139-140.

RevDate: 2018-12-01
CmpDate: 2004-09-30

GARCIA VALCARCEL A (1950)

[Progressive chondritis of the rib cartilages following a subphrenic abscess; failure of bacteriostats in treatment; pathogenesis].

Medicamenta, 8(180):260-261.

RevDate: 2018-12-01
CmpDate: 2004-09-30

RISCHE H, K ROHNE (1950)

[Tests of lichenic bacteriostats].

Das Deutsche Gesundheitswesen, 5(14):432-434.

RevDate: 2021-10-20
CmpDate: 2006-05-31

Diller VM, Tytell AG, Tytell AA, et al (1950)

A SOFT X-RAY MUTANT OF ASPERGILLUS NIGER VAN TIEGHEM.

Plant physiology, 25(2):340-353.

RevDate: 2021-10-20
CmpDate: 2006-05-31

Highkin HR (1950)

CHLOROPHYLL STUDIES ON BARLEY MUTANTS.

Plant physiology, 25(2):294-306.

RevDate: 2020-03-05
CmpDate: 2006-06-01

Dunn LC, S Gluecksohn-Schoenheimer (1950)

Repeated Mutations in One Area of a Mouse Chromosome.

Proceedings of the National Academy of Sciences of the United States of America, 36(4):233-237.

RevDate: 2019-05-13
CmpDate: 2004-09-30

NIGON V, EC DOUGHERTY (1950)

A dwarf mutation in a nematode; a morphological mutant of Rhabditis briggsae, a free-living soil nematode.

The Journal of heredity, 41(4):103-109.

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ESP Quick Facts

ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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This is a must read book for anyone with an interest in invasion biology. The full title of the book lays out the author's premise — The New Wild: Why Invasive Species Will Be Nature's Salvation. Not only is species movement not bad for ecosystems, it is the way that ecosystems respond to perturbation — it is the way ecosystems heal. Even if you are one of those who is absolutely convinced that invasive species are actually "a blight, pollution, an epidemic, or a cancer on nature", you should read this book to clarify your own thinking. True scientific understanding never comes from just interacting with those with whom you already agree. R. Robbins

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Papers in Classical Genetics

The ESP began as an effort to share a handful of key papers from the early days of classical genetics. Now the collection has grown to include hundreds of papers, in full-text format.

Digital Books

Along with papers on classical genetics, ESP offers a collection of full-text digital books, including many works by Darwin (and even a collection of poetry — Chicago Poems by Carl Sandburg).

Timelines

ESP now offers a much improved and expanded collection of timelines, designed to give the user choice over subject matter and dates.

Biographies

Biographical information about many key scientists.

Selected Bibliographies

Bibliographies on several topics of potential interest to the ESP community are now being automatically maintained and generated on the ESP site.

ESP Picks from Around the Web (updated 07 JUL 2018 )