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Bibliography on: Classical Genetics: Mutation

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ESP: PubMed Auto Bibliography 31 Aug 2026 at 01:40 Created: 

Classical Genetics: Mutation

Wikipedia: We now know that, in biology, a mutation is the process that produces heritable change via the permanent alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA or other genetic elements. Mutations result from errors during DNA replication or other types of damage to DNA (such as may be caused by exposure to radiation or carcinogens), which then may undergo error-prone repair, or cause an error during other forms of repair, or else may cause an error during replication. Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce discernible changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. In the early days of classical genetics, work to characterize, model, and understand the phenomenology of mutation were critically important for developing the foundations of modern molecular genetics.

Created with PubMed® Query: 1859:1953[PDAT] AND (mutation OR mutant OR mutagen) NOT pmcbook NOT ispreviousversion

Citations The Papers (from PubMed®)

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RevDate: 2018-12-01
CmpDate: 2003-05-01

ALLISON JB, AW WASE (1952)

The effects of dietary riboflavin and pantothenic acid on the metabolism of 2-aminofluorene.

Cancer research, 12(9):647-650.

RevDate: 2021-03-23
CmpDate: 2003-05-01

IRVIN JL, EM IRVIN (1952)

The interaction of proteins with conjugate pairs molecules or ions; bovine plasma proteins versus a 9-aminoacridine.

The Journal of biological chemistry, 196(2):651-668.

RevDate: 2019-06-27
CmpDate: 2003-05-01

NEMIR P, ZINSSER HH, BEAUDET HA, et al (1952)

Studies on 5-aminoacridine in experimental appendiceal peritonitis.

American journal of surgery, 84(6):663-669.

RevDate: 2019-08-23
CmpDate: 2003-05-01

UNDERWOOD BJ (1952)

Studies of distributed practice. VII. Learning and retention of serial nonsense lists as a function of intralist similarity.

Journal of experimental psychology, 44(2):80-87.

RevDate: 2019-06-19
CmpDate: 2003-05-01

RAY-CHAUDHURI SP, I SARKAR (1952)

Frequency of dicentric bridges in Meiosis in the grasshopper Gesonia punctifrons, produced by different dosages of x-rays.

Science (New York, N.Y.), 116(3018):479-482.

RevDate: 2018-12-01
CmpDate: 2003-05-01

HAY ED (1952)

The role of epithelium in amphibian limb regeneration, studied by haploid and triploid transplants.

The American journal of anatomy, 91(3):447-481.

RevDate: 2019-07-03
CmpDate: 2003-05-01

HUNTER AR (1952)

Strychnine dimethyl sulphate.

Anaesthesia, 7(4):206-210.

RevDate: 2019-06-29
CmpDate: 2003-05-01

OGUR M, MINCKLER S, LINDEGREN G, et al (1952)

The nucleic acids in a polyploid series of Saccharomyces.

Archives of biochemistry and biophysics, 40(1):175-184.

RevDate: 2019-05-14
CmpDate: 2003-05-01

MATTISON BF (1952)

The health officer's job, sense and nonsense.

American journal of public health and the nation's health, 42(12):1507-1512.

RevDate: 2018-12-01
CmpDate: 2003-05-01

STONE CA, KOMRAD EL, ER LOEW (1952)

Adrenergic blocking properties of N-ethyl-N-(2-chloroethyl)-9-fluorenamine hydrochloride.

Archives internationales de pharmacodynamie et de therapie, 92(1):7-12.

RevDate: 2019-06-29
CmpDate: 2003-05-01

WITKOP B, S GOODWIN (1952)

Significance and rearrangements of quinol models of tyrosine metabolites.

Experientia, 8(10):377-379.

RevDate: 2018-12-01
CmpDate: 2003-05-01

ALONSO FERNANDEZ F (1952)

[Diagnostic significance of unilateral inversion of the length of the index and ring fingers].

Medicina, 20(5 2):313-316.

RevDate: 2019-06-18
CmpDate: 2003-05-01

POMPER S (1952)

Isolation of triploid Saccharomyces cerevisiae.

Nature, 170(4334):892-893.

RevDate: 2018-12-01
CmpDate: 2003-05-01

DOGLIONI L (1952)

[Observations on the use of acridine orange in histological applications of fluorescent microscopy].

Rivista di anatomia patologica e di oncologia, 5(8):983-990.

RevDate: 2019-06-19
CmpDate: 2003-05-01

WASE AW, ALLISON JB, JF MIGLIARESE (1952)

The effect of 2-aminofluorene on the utilization of S35 DL-methionine.

Science (New York, N.Y.), 116(3020):536-537.

RevDate: 2018-12-01
CmpDate: 2003-05-01

PATANE L (1952)

[Enteric ceca and mesointestinal glands of Cirripeds].

Bollettino della Societa italiana di biologia sperimentale, 28(6):1233-1235.

RevDate: 2021-02-10
CmpDate: 2003-05-01

GOLDSTEIN MS (1952)

The in vitro effects of sodium azide on tissues of normal and thyroid-fed rats.

The Journal of biological chemistry, 199(2):923-928.

RevDate: 2018-12-01
CmpDate: 2003-05-01

VIVIEN J (1952)

[The role of the hypophysis in the determinism of ovarian involution and sexual inversion in Xiphiphorus].

Journal de physiologie, 44(2):349-351.

RevDate: 2019-11-07
CmpDate: 2003-05-01

BIRD MJ, OG FAHMY (1953)

Cytogenetic analysis of the action of carcinogens and tumour inhibitors in Drosophila melanogaster. I. 1:2, 3:4-diepoxybutane.

Proceedings of the Royal Society of London. Series B, Biological sciences, 140(901):556-578.

RevDate: 2018-12-01
CmpDate: 2003-05-01

TONELLI A (1952)

[Opsonidine; as Factor Op. 84, which potentializes bacteriostasis, in its clinical application].

La Semana medica, 101(6):188-194.

RevDate: 2018-12-01
CmpDate: 2003-05-01

LUNDQVIST M (1952)

[Sense and nonsense of old popular remedies].

Svensk farmaceutisk tidskrift, 56(33):681-688.

RevDate: 2019-06-28
CmpDate: 2003-05-01

KEATS AS, HK BEECHER (1953)

The analgesic effectiveness of morphine solutions containing sodium bisulfite.

Anesthesiology, 14(2):140-142.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GRUNDLAND I (1953)

[Study of antituberculous synthetics from the standpoint of bacteriostasis in vitro; bacteriostatic activity of isonicotinic acid hydrazide and its antituberculous activity in vivo].

Comptes rendus hebdomadaires des seances de l'Academie des sciences, 236(1):152-154.

RevDate: 2018-12-01
CmpDate: 2003-05-01

RAYMOND-HAMET (1953)

[Inversion by quinine of the hypertensive action of adrenalin].

Comptes rendus hebdomadaires des seances de l'Academie des sciences, 236(2):248-250.

RevDate: 2018-12-01
CmpDate: 2003-05-01

VIVINO AE, G RITTER (1953)

Treatment of dysmenorrhea with a dioxolane.

The Medical annals of the District of Columbia, 22(3):117-8; passim.

RevDate: 2019-06-18
CmpDate: 2003-05-01

DARLINGTON CD (1953)

Polyploidy in animals.

Nature, 171(4344):191-194.

RevDate: 2018-12-01
CmpDate: 2003-05-01

STOCKINGER L (1952)

[Vital staining of tissue cultures with acridin orange].

Zeitschrift fur mikroskopisch-anatomische Forschung, 59(1-3):304-325.

RevDate: 2018-12-01
CmpDate: 2003-05-01

MORICARD R (1952)

[Reflections on the definition of the O stage of epitheliomas of the cervix uteri; chromosome abnormalities].

Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise, 4(5):844-856.

RevDate: 2018-12-01
CmpDate: 2003-05-01

BIANCO A (1952)

[Chronic & complete inversion of the uterus; case report].

Revista De Ginecologia Y Obstetricia, 46(2 5):737-740.

RevDate: 2018-12-01
CmpDate: 2003-05-01

LUNDQVIST M (1952)

[Sense and nonsense of old popular remedies. II].

Svensk farmaceutisk tidskrift, 56(35):721-728.

RevDate: 2019-08-23
CmpDate: 2003-05-01

UNDERWOOD BJ (1953)

Studies of distributed practice. VIII. Learning and retention of paired nonsense syllables as a function of intralist similarity.

Journal of experimental psychology, 45(3):133-142.

RevDate: 2019-08-23
CmpDate: 2003-05-01

UNDERWOOD BJ (1953)

Studies of distributed practice. XI. An attempt to resolve conflicting facts on retention of serial nonsense lists.

Journal of experimental psychology, 45(5):355-359.

RevDate: 2019-06-18
CmpDate: 2003-05-01

VLITOS AJ, KING LF, LJ AUDUS (1953)

Fate of sodium 2, 4-dichloro-phenoxy-ethyl-sulphate in the soil.

Nature, 171(4351):523-524.

RevDate: 2019-06-18
CmpDate: 2003-05-01

DAVIES EW (1953)

Polyploidy in Primula farinosa L.

Nature, 171(4354):659-660.

RevDate: 2019-06-29
CmpDate: 2003-05-01

SARACHEK A, WH LUCKE (1953)

Ultraviolet inactivation of Polyploid Saccharomyces.

Archives of biochemistry and biophysics, 44(2):271-279.

RevDate: 2021-02-10
CmpDate: 2003-05-01

FALES FW (1953)

The effect of sodium azide on alcoholic fermentation.

The Journal of biological chemistry, 202(1):157-167.

RevDate: 2019-06-18
CmpDate: 2003-05-01

LUCKE WH, A SARACHEK (1953)

X-ray inactivation of polyploid Saccharomyces.

Nature, 171(4362):1014-1015.

RevDate: 2018-12-01
CmpDate: 2003-05-01

HOFFMANN CR (1953)

Indications for the use of diphenmethanil methyl sulfate (prantal) in the treatment of peptic ulcer.

American practitioner and digest of treatment, 4(7):464-468.

RevDate: 2018-12-01
CmpDate: 2003-05-01

BOGEN HJ (1953)

[Staining, injuring and killing of yeast cells by acridine orange].

Archiv fur Mikrobiologie, 18(2):170-197.

RevDate: 2018-12-01
CmpDate: 2003-05-01

WEAVER G, JH BELTON (1953)

Acute incomplete inversion of the uterus.

Canadian Medical Association journal, 69(2):154-155.

RevDate: 2018-12-01
CmpDate: 2003-05-01

STAIGER H, H GLOOR (1952)

[Inhibition of mitosis and polyploidy atrributable to a lethal factor in Drosophila hydei].

Chromosoma, 5(3):221-245.

RevDate: 2018-12-01
CmpDate: 2003-05-01

MECHELKE F (1952)

[The origin of polyploid nuclei in the antheric tapetum of Antirrhinum majus L].

Chromosoma, 5(3):246-295.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GRANT V (1952)

Cytogenetics of the hybrid Gilia millefoliata x achilleaefolia. I. Variations in meiosis and polyploidy rate as affected by nutritional and genetic conditions.

Chromosoma, 5(4):372-390.

RevDate: 2021-05-26
CmpDate: 2003-05-01

BERGER H, HASS FL, WYSS O, et al (1953)

Effect of sodium azide on radiation damage and photoreactivation.

Journal of bacteriology, 65(5):538-543.

RevDate: 2018-12-01
CmpDate: 2003-05-01

UBRIG H (1953)

[A new suppository foundation on the basis of a firm meltable emulsion].

Die Pharmazie, 8(3):219-220.

RevDate: 2020-12-09
CmpDate: 2003-05-01

LUNDQVIST M (1953)

[Sense and nonsense of old popular remedies. III].

Svensk farmaceutisk tidskrift, 57(6):103-112.

RevDate: 2018-12-01
CmpDate: 2003-05-01

SJOSTRAND T (1953)

The oxidation of haemoglobin in the presence of NaN3.

Acta physiologica Scandinavica, 28(2-3):244-254.

RevDate: 2018-12-01
CmpDate: 2003-05-01

BOREUS LO, F SANDBERG (1953)

A comparison of some pharmacological effects of acetophenetidin and N-acetyl p-aminophenol.

Acta physiologica Scandinavica, 28(2-3):261-265.

RevDate: 2018-12-01
CmpDate: 2003-05-01

BOREUS LO, F SANDBERG (1953)

The analgesic action of n-acetyl p-aminophenol and its combination with some other substances.

Acta physiologica Scandinavica, 28(2-3):266-271.

RevDate: 2019-08-27
CmpDate: 2003-05-01

MARKS MM (1953)

Clinical re-evaluation of dorbane in the treatment of functional constipation.

The American journal of digestive diseases, 20(8):240-242.

RevDate: 2018-12-01
CmpDate: 2003-05-01

LIENHART R (1953)

[Temporary sex inversion, at time of puberty, in the female domestic pigeon; heredity of this phenomenon].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 147(5-6):472-474.

RevDate: 2018-12-01
CmpDate: 2003-05-01

HILDEBRAND G (1953)

[Depressor effects of adrenalin and adrenalin inversion].

Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 218(1-2):133-134.

RevDate: 2018-12-01
CmpDate: 2003-05-01

WEISSMANN C (1953)

[Vital staining of amphibian larvae with acridine orange].

Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 38(4):374-408.

RevDate: 2019-06-29
CmpDate: 2003-05-01

DENTON CA, WL KELLOGG (1953)

The vitamin B12 activity of eggs and some materials as affected by extraction in the presence of sodium cyanide or sodium bisulfite.

Archives of biochemistry and biophysics, 46(1):105-109.

RevDate: 2019-06-29
CmpDate: 2003-05-01

INGRAHAM JL, ROBY TO, JH PETERSON (1953)

Effect of 2,4-dinitrophenol and sodium azide on host cell metabolism and influenza A virus.

Archives of biochemistry and biophysics, 46(1):215-220.

RevDate: 2023-12-13
CmpDate: 2003-05-01

LEFEVRE J, H HESLOT (1953)

[Incomplete polyploidy and phenotypic variations induced by colchicine in Nicotiana hybrids].

Comptes rendus hebdomadaires des seances de l'Academie des sciences, 237(11):576-578.

RevDate: 2018-12-01
CmpDate: 2003-05-01

ROSEMBERG J, CAMPOS NS, JN AUN (1953)

[Current status of knowledge of inversion of the Mitsuda reaction by oral BCG].

Hospital (Rio de Janeiro, Brazil), 44(1):33-73.

RevDate: 2019-07-10
CmpDate: 2003-05-01

JACKSON BP, JM ROWSON (1953)

Alkaloid biogenesis in tetraploid stramonium.

The Journal of pharmacy and pharmacology, 5(10):778-793.

RevDate: 2019-06-18
CmpDate: 2003-05-01

LA COUR LF, A RUTISHAUSER (1953)

Chromosome breakage experiments with endosperm :sub-chromatid breakage.

Nature, 172(4376):501-502.

RevDate: 2018-12-01
CmpDate: 2003-05-01

CLEMENT R (1953)

[Ambiguous sexual type; gynandrism].

Revista espanola de pediatria, 9(51):547-558.

RevDate: 2018-12-01
CmpDate: 2003-05-01

DE PEVERELLI VM (1953)

[Inversion of germinal layers in rodents of the genus Ctenomys].

La Semana medica, 103(1):16-20; passim.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GRIZZLE CO (1953)

Effects of sodium azide on the blood pressure of rats.

Stanford medical bulletin, 11(3):145-148.

RevDate: 2018-12-01
CmpDate: 2003-05-01

VON BRANDT H, W DITTRICH (1953)

[Induced breaks of the ring chromosome Xc2 of Drosophila melanogaster after irradiation with x-rays and fast electrons].

Strahlentherapie, 91(1):149-156.

RevDate: 2026-01-28
CmpDate: 2003-05-01

KNAPP R (1953)

[Relations between polyploidy, distribution and systematic and sociological position of plant species in the Middle Europe].

Zeitschrift fur induktive Abstammungs- und Vererbungslehre, 85(2):163-179.

RevDate: 2018-12-01
CmpDate: 2003-05-01

MORRIS GE (1953)

Synthetic rubbers; their chemistry and dermatological aspects.

A.M.A. archives of industrial hygiene and occupational medicine, 8(6):540-546.

RevDate: 2018-12-01
CmpDate: 2003-05-01

FORMAN L (1953)

A note on the depigmentary properties of monobenzylether of hydroquinone.

The British journal of dermatology, 65(11):406-409.

RevDate: 2019-06-18
CmpDate: 2003-05-01

DA CUNHA AB (1953)

Chromosomal inversions with sex-limited effects.

Nature, 172(4383):815-816.

RevDate: 2019-06-18
CmpDate: 2003-05-01

ROSIN A, F DOLJANSKI (1953)

Effect of hydroquinone on mitosis.

Nature, 172(4390):1151.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GANSHIRT H (1953)

[Isolation of aristolochic acid from various Aristolochiaceae and its quantitative determination].

Die Pharmazie, 8(7):584-592.

RevDate: 2018-12-01
CmpDate: 2003-05-01

DEUFEL J, H GANSHIRT (1953)

[Studies on the effect of aristolochic acid on bacteria and cell division of Vicia faba L].

Die Pharmazie, 8(8):679-682.

RevDate: 2018-12-01
CmpDate: 2003-05-01

MOIR JC (1953)

Complete inversion of the bladder through a vesico-vaginal fistula of twenty-seven years' duration.

Proceedings of the Royal Society of Medicine, 46(10):844-845.

RevDate: 2019-06-19
CmpDate: 2003-05-01

STORMONT C, WEIR WC, LL LANE (1953)

Erythrocyte mosaicism in a pair of sheep twins.

Science (New York, N.Y.), 118(3075):695-696.

RevDate: 2018-12-01
CmpDate: 2003-05-01

CAHEN P, FROMENT R, LEHMANN M, et al (1953)

[Inversion of the T wave in right precordial leads by exercise tests in mitral stenosis].

Archives des maladies du coeur et des vaisseaux, 46(9):820-827.

RevDate: 2018-12-01
CmpDate: 2003-05-01

PISANTY J, A NAVA (1953)

[Digitalis-like effect of acridine orange].

Archivos del Instituto de Cardiologia de Mexico, 23(4):516-524.

RevDate: 2018-12-01
CmpDate: 2003-05-01

PARMENTIER R (1953)

[Fusorial action of hydroquinone in the rabbit].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 147(9-10):935-937.

RevDate: 2019-06-29
CmpDate: 2003-05-01

MUNDKUR BD (1953)

Interphase nuclei and cell sizes in a polyploid series of Saccharomyces.

Experientia, 9(10):373-374.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GIUGIARO A, D CASTELLI (1953)

[Trimethyl (methylphenyldodecyl) ammonium methyl sulfate in preoperative antisepsis].

Minerva chirurgica, 8(18):716-722.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GRIANTI V, E BARTALINI (1953)

[The use of lipotropic substances, complex B and liver extracts in some cases of industrial liver disease].

Rassegna di medicina industriale e di igiene del lavoro, 22(4-5):220-232.

RevDate: 2018-12-01
CmpDate: 2003-05-01

PARMENTIER R, P DUSTIN (Jr) (1953)

[On the mechanism of the mitotic abnormalities induced by hydroquinone in animal tissues].

Revue belge de pathologie et de medecine experimentale, 23(1):20-30.

RevDate: 2018-12-01
CmpDate: 2003-05-01

NOWINSKI WW, PL EWING (1953)

Effect of tetraethyl thiuram disulfide (antabuse) on the alcohol metabolism in vivo.

Texas reports on biology and medicine, 11(4):597-601.

RevDate: 2018-12-01
CmpDate: 2003-05-01

MILOSEVIC MP, DB TODOROVIC (1953)

Influence of sodium bisulphite on the absorption rate of acetylcholine and of 1-noradrenaline.

Acta medica Iugoslavica, 7(3):197-203.

RevDate: 2018-12-01
CmpDate: 2003-05-01

GHIZZARDI B (1953)

Inversion of nuclear index in neoplastic disease.

Bollettino - Societa medico chirurgica Cremona, 7(1-4):51-56.

RevDate: 2018-12-01
CmpDate: 2003-05-01

YOSIDA TH (1953)

[Karyological study on the tetraploid tumors in the rat and the mouse].

Gan, 44(2-3):143-144.

RevDate: 2026-01-28
CmpDate: 2003-05-01

MUHLEMANN H (1953)

[Anthraquinone and anthraquinone glycosides; the synthesis of Chrysazinhydroquinone-1-glycoside and chrysazin-9-anthrone-1-glycoside].

Pharmaceutica acta Helvetiae, 28(11):313-319.

RevDate: 2020-09-30
CmpDate: 2003-05-01

CARLSON AJ, NR BREWER (1953)

Toxicity studies on hydroquinone.

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 84(3):684-688.

RevDate: 2026-01-28
CmpDate: 2003-05-01

STUMM-ZOLLINGER E (1953)

[Comparative studies on inversion frequency in Drosophila subobscura in populations of Switzerland and Southwest Europe].

Zeitschrift fur induktive Abstammungs- und Vererbungslehre, 85(3):382-407.

RevDate: 2018-12-01
CmpDate: 2003-05-01

PARMENTIER R, G ASTALDI (1953)

[First research on the effects of hydroquinone on proliferation of human bone marrow cells cultivated in vitro].

Bollettino della Societa italiana di biologia sperimentale, 29(7):1315-1317.

RevDate: 2018-12-01
CmpDate: 2003-05-01

OMODEO P (1953)

[Considerations on polyploidy in earthworms].

Bollettino della Societa italiana di biologia sperimentale, 29(7):1437-1439.

RevDate: 2018-12-01
CmpDate: 2003-05-01

STOCKER A (1953)

[Neurosis, inversion, perversion and guilt].

Praxis, 42(51):1065-1073.

RevDate: 2018-12-01
CmpDate: 2004-02-15

HICKS SP (1950)

Brain metabolism in vivo. II. The distribution of lesions caused by azide, malononitrile, plasmocid and dinitrophenol poisoning in rats.

A.M.A. archives of pathology, 50(5):545-561.

RevDate: 2018-12-01
CmpDate: 2004-02-15

MOURIQUAND G, EDEL V, R CHIGHIZOLA (1950)

[Inversion by contact with air of the action of aneurin on the vestibular chronaxia].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 144(7-8):548-549.

RevDate: 2019-06-29
CmpDate: 2004-02-15

SOLLNER R (1950)

[Intraspecific polyploid in Cerastium arvense L. and chromosome number of several other Cerastium].

Experientia, 6(9):335-337.

RevDate: 2022-12-07
CmpDate: 2004-02-15

CURCI G (1950)

[Fate in the guinea pig tubercle bacilli in streptomycin bacteriostasis].

Archivio di tisiologia e delle malattie dell'apparato respiratorio, 5(4):337-340.

RevDate: 2019-05-09
CmpDate: 2004-02-15

CUNNINGHAM L, GRIFFIN AC, JM LUCK (1950)

Polyploidy and cancer; the desoxypentosenucleic acid content of nuclei of normal, precancerous, and neoplastic rat tissues.

The Journal of general physiology, 34(1):59-63.

The average desoxypentosenucleic acid content of individual nuclei was determined for various normal and tumor tissues, and for livers showing precancerous changes, in the rat. With certain exceptions attributable to polyploidy, the values were practically indistinguishable from each other and from values reported for cell nuclei of other mammals. The amount of this nucleic acid in diploid cells of the rat appears to be a constant, nearly equal to 6 x 10(-6) micrograms. Findings of increased concentrations of this nucleic acid in tissues showing preneoplastic or neoplastic changes therefore confirm histological observations of increased cellularity and polyploidy in such tissues.

RevDate: 2019-06-18
CmpDate: 2004-02-15

RACE RR, R SANGER (1950)

A probable deletion in a human Rh chromosome.

Nature, 166(4221):520.

RevDate: 2018-12-01
CmpDate: 2004-02-15

STEINEGGER E, W NEUBURGER (1950)

[Experiments on heteroploidy in medicinal plants. 11. Effect of polyploidy on the alkaloid content of Lobelia syphilitica].

Pharmaceutica acta Helvetiae, 25(7-8):237-240.

RevDate: 2019-06-19
CmpDate: 2004-02-15

GILES NH, AV BEATTY (1950)

The effect of X-irradiation in oxygen and in hydrogen at normal and positive pressures on chromosome aberration frequency in Tradescantia microspores.

Science (New York, N.Y.), 112(2918):643-645.

RevDate: 2018-12-01
CmpDate: 2004-02-15

BLANCHARD PH, N ALBON (1950)

The inversion of sucrose; a complication.

Archives of biochemistry, 29(1):220-222.

RevDate: 2018-12-01
CmpDate: 2004-02-15

HAY ED (1950)

The role of epidermis in amphibian regeneration as revealed by triploid and haploid transplants to diploid limbs.

The Biological bulletin, 99(2):351-352.

RevDate: 2019-09-22
CmpDate: 2004-02-15

CRILE G, AH ROBNETT (1951)

Treatment of pharyngo-esophageal diverticulum by inversion of the sac.

Cleveland Clinic quarterly, 18(1):42-47.

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ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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Electronic Scholarly Publishing
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Papers in Classical Genetics

The ESP began as an effort to share a handful of key papers from the early days of classical genetics. Now the collection has grown to include hundreds of papers, in full-text format.

Digital Books

Along with papers on classical genetics, ESP offers a collection of full-text digital books, including many works by Darwin and even a collection of poetry — Chicago Poems by Carl Sandburg.

Timelines

ESP now offers a large collection of user-selected side-by-side timelines (e.g., all science vs. all other categories, or arts and culture vs. world history), designed to provide a comparative context for appreciating world events.

Biographies

Biographical information about many key scientists (e.g., Walter Sutton).

Selected Bibliographies

Bibliographies on several topics of potential interest to the ESP community are automatically maintained and generated on the ESP site.

ESP Picks from Around the Web (updated 28 JUL 2024 )