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About | Classical Genetics | Timelines | What's New | What's Hot

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The Electronic Scholarly Publishing Project: Providing access to classic scientific papers and other scholarly materials, since 1993. More About:  ESP | OUR CONTENT | THIS WEBSITE | WHAT'S NEW | WHAT'S HOT

ESP Timelines

Comparative Timelines

The ESP Timeline (one of the site's most popular features) has been completely updated to allow the user to select (using the timeline controls above each column) different topics for the left and right sides of the display.

Select:

New Left Column

New Left Column

Dates

Decade

New Right Column

New Right Column

At a Cold Spring Harbor Symposium, Ernst Mayr argues that all hominid specimens so far found should be categorized in the genus Homo: H. transvaalensis, H. erectus, and H. sapiens.

E. Chargaff lays the foundations for nucleic acid structural studies by his analytical work. He demonstrates for DNA that the numbers of adenine and thymine groups are always equal and so are the numbers of guanine and cytosine groups. These findings later suggest to Watson and Crick that DNA consists of two polynucleotide strands joined by hydrogen bonding between A and T and between G and C.

E. M. Lederberg discovers lambda, the first viral episome of E. coli.

1950

Earl (Bertrand Arthur William) Russell awarded the Nobel Prize in Literature "in recognition of his varied and significant writings in which he champions humanitarian ideals and freedom of thought".

The first Elliott 152 computer appeared

Zuse sold first Z4 computer

image All about Eve wins Academy Award for best picture. Three of the year s five best picture nominees were dominated by great female performances: Born Yesterday, Sunset Blvd. and All About Eve. But Joseph Mankiewicz s witty tale about Broadway competition was the one that ended up in the winner s circle.

Barbara McClintock publishes a paper describing "jumping" genes that can move around within an organism's genome.

1951

Pär Fabian Lagerkvist awarded the Nobel Prize in Literature "for the artistic vigour and true independence of mind with which he endeavours in his poetry to find answers to the eternal questions confronting mankind".

image Painting by Salvador Dal : Christ of Saint John of the Cross depicts Jesus Christ on the cross in a darkened sky floating over a body of water complete with a boat and fishermen. Although it is a depiction of the crucifixion, it is devoid of nails, blood, and a crown of thorns, because, according to Dal , he was convinced by a dream that these features would mar his depiction of Christ. Also in a dream, the importance of depicting Christ in the extreme angle evident in the painting was revealed to him.

image On May 24, a mob of 3500 whites attempt to prevent a black family from moving into an apartment in Cicero, Illinois. Illinois Gov. Adlai Stevenson calls out the Illinois National Guard to protect the family and restore order.

On May 24, the United States Supreme Court rules that racial segregation in District of Columbia restaurants is unconstitutional.

Ferranti Mark 1 delivered to Manchester University

LEO I computer became operational

The first UNIVAC was delivered

UNIVAC-1 goes online

image An American in Paris wins Academy Award for best picture. This Vincent Minnelli musical starring Gene Kelly, was a surprise winner. Producer Arthur Freed took home the Oscar, starting the Academy s new policy of giving the award to an individual producer, rather than the studio. After Gone with the Wind, this was the second best-pic winner in color.

A. D. Hershey and M. Chase demonstrate that the DNA of phage enters the host, whereas most of the protein remains behind.

F. Sanger and his colleagues work out the complete amino acid sequence for the protein hormone insulin, and show that it contains two polypeptide chains held together by disulfide bridges.

J. Lederberg and E. M. Lederberg invent the replica plating technique.

N. D. Zinder and J. Lederberg describe transduction in Salmonella.

1952

image Ralph Ellison publishes Invisible Man.

François Mauriac awarded the Nobel Prize in Literature "for the deep spiritual insight and the artistic intensity with which he has in his novels penetrated the drama of human life".

image Painting by Jackson Pollock: Number 11, 1952, also known as Blue Poles, is one of the most famous works by American artist Jackson Pollock. It was purchased amid controversy by the National Gallery of Australia in 1973 and today remains one of the gallery's major paintings. At the time of the painting's creation, Pollock preferred not to assign names to his works, but rather numbers; hence, the original title of the painting was simply "Number 11"' or "No. 11" for the year 1952. In 1954, the new title Blue Poles was first seen at an exhibition at the Sidney Janis Gallery and reportedly originated from Pollock himself. According to art historian Dennis Phillips, the specific rather than ambiguous title "limits our field of comprehension and does the painting a singular disservice. Because we look for the poles and miss much of the rest, the name is simply too distracting."

CBS News Uses UNIVAC Computer to Predict Election

Grace Hopper completes the A-0 Compiler

Heinz Nixdorf founded Nixdorf Computer

Bwana Devil, a low-budget polarized 3-D film, premieres in late November and starts a brief 3-D craze that begins in earnest in 1953 and fades away during 1954.

Russian geologist Boris Sokolov establishes the term Vendian. Based on rock strata in the Soviet Union, it designates the period immediately preceding the Cambrian, coinciding with fossils found near the Ediacara Hills.

image The Greatest Show on Earth wins Academy Award for best picture. Director Cecil B. DeMille was a showman since the silent days of movies, but this was his first to take the Best Picture Academy Award, with his colorful and gaudy spectacle about life in the circus.

image image J. D. Watson and F. H. C. Crick propose a model for DNA comprised of two helically intertwined chains tied together by hydrogen bonds between the purines and pyrimidines.

W. Hayes discovers polarized behavior in bacterial recombinations. He isolates the Hfr H strain of E. coli and shows that certain genes are readily transferred from Hfr to F- bacteria, whereas others are not.

1953

Sir Winston Leonard Spencer Churchill awarded the Nobel Prize in Literature "for his mastery of historical and biographical description as well as for brilliant oratory in defending exalted human values".

image Painting by Francis Bacon: Study after Velázquez's Portrait of Pope Innocent X shows a distorted version of the Portrait of Innocent X painted by Spanish artist Diego Velázquez in 1650. The work is one of a series of over 45 variants of the Velázquez painting which Bacon executed throughout the 1950s and early 1960s. The picture was described by Gilles Deleuze as an example of creative re-interpretation of the classical. When asked why he was compelled to revisit the subject so often, Bacon replied that he had nothing against the Popes, that he merely sought "an excuse to use these colours, and you can't give ordinary clothes that purple colour without getting into a sort of false fauve manner".

IBM announces the Model 650 computer

Jay Forrester installed magnetic core memory at MIT

image Dwight D. Eisenhower becomes thirty-fourth president of the United States.

Piltdown Man is determined to be a hoax: the jaw of an ape and a human skull.

Fiesel Houtermans and Clair Patterson publish independent estimates inferring the age of the Earth through radiometric dating of meteorites. Both estimates are over 4.5 billion years.

image From Here to Eternity wins Academy Award for best picture. Daniel Taradash adapted James Jones novel into a great screenplay, augmented by Fred Zinnemann s smart direction. Burt Lancaster topped a strong cast in the tale of military lives in Hawaii just before the bombing of Pearl Harbor.

(no entry for this year)

1954

Ernest Miller Hemingway awarded the Nobel Prize in Literature "for his mastery of the art of narrative, most recently demonstrated in The Old Man and the Sea, and for the influence that he has exerted on contemporary style".

image Painting by Jasper Johns: Flag is an encaustic painting created when Johns was 24 (1954-55), two years after he was discharged from the US Army. This painting was the first of many works that Johns has said were inspired by a dream of the U.S. flag in 1954. It is arguably the painting for which Johns is best known. The US flag was in the news repeatedly in 1954. The McCarthy hearings came to a close on 17 June 1954, only three days after Flag Day. On Flag Day, U.S. President Dwight D. Eisenhower signed an amendment to the pledge of allegiance to add the words "under God." The New York Times ran article on facts and myths associated with the flag on the day before Flag Day, and then an article on the "discipline" of the flag on Flag Day itself, saying, with reference to a national air-raid drill "we are all soldiers now". Francis Scott Key, composer of "The Star Spangled Banner", was born in 1779, 175 years before 1954. The Iwo Jima Marine Memorial at Arlington National Cemetery, with its large US flag, was dedicated on 11 November 1954. Johns and his father were both named after Sergeant William Jasper, who saved the fallen flag of the Americans at Fort Moultrie in the American Revolutionary War. The work measures 42.2 inches by 60.6 inches. It is made using encaustic, oil paint, and newsprint collage on three separate canvases, mounted on a plywood board. The painting reflects the three colors of the US flag: red, white and blue; the flag is depicted in the form it took between 1912 and 1959, with 48 white stars on a blue canton representing the then-US states (excluding Alaska and Hawaii), and with thirteen red and white stripes. Newsprint is visible under the stripes. Reading the texts, it is clear that the newsprint was not selected at random: Johns steered clear of headlines, or national or political news, and used inconsequential articles or adverts. The painting has a rough-textured surface, and the 48 stars are not identical. It is dated 1954 on its reverse.

On May 17, the United States Supreme Court, in Brown vs the Board of Education, declares segregation in all public schools in the United States unconstitutional, nullifying the earlier judicial doctrine of "separate but equal."

20th September First FORTRAN Program Runs

IBM Announces Model 705 Computer

Jack Tramiel starts Commodore

Leica M Introduced

Elso Barghoorn and Stanley Tyler report the discovery of bacterial cells in Canadian rock formations that are nearly 2 billion years old.

Philip Abelson and his team detect amino acids in fish that are over 300 million years old.

image On the Waterfront wins Academy Award for best picture. Marlon Brando won his first Oscar as Terry Malloy, a New York dock worker. Elia Kazan directed from a script by Budd Schulberg, both of whom were targeted by the Hollywood blacklist; some have seen this film as a metaphor for their experiences and an explanation of their actions.

image S. Benzer works out the fine structure of the rII region of phage T4 of E. coli, and coins the terms CISTRON,RECON, and MUTON.

1955

Halldór Kiljan Laxness awarded the Nobel Prize in Literature "for his vivid epic power which has renewed the great narrative art of Iceland".

image Chuck Berry records Maybellene.

image Rosa Parks refuses to relinquish her bus seat to a white man on December 1, initiating the Montgomery bus boycott. Soon afterward, Martin Luther King, Jr., becomes the leader of the boycott.

image Fourteen-year-old Chicago resident Emmett Till is lynched in Money, Mississippi, on August 28.

Apple Co-Founder Steve Jobs is Born

Bill Gates, cofounder of Microsoft Corporation, was born

English Electric Deuce Computers introduced

ENIAC is retired

image Professional pipefitter and amateur paleontologist Francis Tully finds an enigmatic fossil near Morris, Illinois. Dating from about 300 million years ago, the fossil will be formally named Tullimonstrum gregarium and nicknamed the Tully monster. Although it will defy classification for decades, it will nevertheless be named the state fossil of Illinois.

image Marty wins Academy Award for best picture. The intimate character study made Oscar history because it was an adaptation of a TV drama and because it was the first film whose awards campaign costs ($400,000) surpassed its production budget ($340,000).

F. Jacob and E. L. Wollman are able experimentally to interrupt the mating process in E. coli and show that a piece of DNA is inserted from the donor bacterium into the recipient.

1956

Juan Ramón Jiménez awarded the Nobel Prize in Literature "for his lyrical poetry, which in Spanish language constitutes an example of high spirit and artistical purity".

image Collage by Richard Hamilton: Just what is it that makes today's homes so different, so appealing? measures 10.25 in (260 mm) × 9.75 in (248 mm). The work is now in the collection of the Kunsthalle Tübingen, Tübingen, Germany. It was the first work of pop art to achieve iconic status. Just what is it that makes today's homes so different, so appealing? was created in 1956 for the catalogue of the exhibition This Is Tomorrow in London, England in which it was reproduced in black and white. In addition, the piece was used in posters for the exhibit. Hamilton and his friends John McHale and John Voelcker had collaborated to create the room that became the best-known part of the exhibition.

First keyboard used to input data

IBM brings out the Magnetic Disk Memory

IBM introduces the IBM 350

Jay Forrester Receives Patent on "Core" Memory

Pegasus, produced by Ferranti Ltd., went into service in March 1956

Wang Sells Core Memory Patent to IBM

Fifteen-year-old English schoolgirl Tina Negus finds a specimen of the fossil species that will later be named Charnia masoni, from the geologic period that will later be named the Ediacaran. Unfortunately, Negus can't convince her geography teacher that the fossil she has found is Precambrian and gives up, leaving the fossil to be extracted by local schoolboy Roger Mason the next year.

Keith Runcorn publishes a paper describing polar wandering based on paleomagnetic studies of Europe and North America. He suggests continental drift, but his paper attracts little attention.

Paleontologist M. W. de Laubenfels publishes a paper suggesting that the dinosaurs were driven to extinction by a meteorite impact. His paper will not be taken seriously, but this hypothesis will be presented again in 1980 with more compelling evidence.

Brian Logan and fellow geologists find living stromatolites in Shark Bay, Australia. The find is somewhat surprising as stromatolites have no defenses against mouth-bearing organisms and have probably been relatively rare since the Cambrian Period.

image Around the World in 80 Days wins Academy Award for best picture. Producer Michael Todd coined the term cameo to describe the multiple stars appearing briefly in small roles. This film, adapted from Jules Verne s novel, starred David Niven, Cantinflas and Shirley MacLaine, and featured dozens of stars like Frank Sinatra, Buster Keaton and Marlene Dietrich in brief (and sometimes wordless) appearances.

Francis Crick proposes the "central dogma" of genetic information transfer: DNA specifies RNA and RNA specifies cell proteins.

V. M. Ingram reports that normal and sickle-cell hemoglobin differ by a single amino acid substitution.

1957

Albert Camus awarded the Nobel Prize in Literature "for his important literary production, which with clear-sighted earnestness illuminates the problems of the human conscience in our times".

Congress passes the Civil Rights Act of 1957, the first legislation protecting black rights since Reconstruction.

In September, Pres. Dwight D. Eisenhower sends federal troops to Little Rock, Arkansas, to ensure the enforcement of a federal court order to desegregate Central High School and to protect nine African-American students enrolled as part of the order.

BCS - British Computer Society is Founded

CDC Introduces 1604 Computer

DEC is founded

Ferranti Mercury Introduced

FORTRAN-1 is formally published

May 1957 LEO II Installed

First Asahi Pentax SLR introduced.

First digital computer acquisition of scanned photographs, by Russell Kirsch et al. at the U.S. National Bureau of Standards (now the NIST).

The Soviet Union launches Sputnik.

image The Bridge on the River Kwai wins Academy Award for best picture. The big-scale drama, about the insanity of war, was directed by David Lean. The screenplay was credited to Pierre Boule, who wrote the novel. But in 1984, the Academy updated their records to acknowledge that the script was written by Michael Wilson and Carl Foreman, who had been blacklisted at the time.

Frederick Sanger receives a Nobel Prize in Chemistry for his work on the structure of proteins, especially that of insulin.

George W. Beadle, Edward L. Tatum, and Joshua Lederberg share a Nobel Prize in Medicine for Beadle and Tatum's discovery that genes act by regulating definite chemical events, and for Lederberg's discoveries concerning genetic recombination and the organization of the genetic material of bacteria.

image F. H. C. Crick suggests that during protein formation the amino acid is carried to the template by an adaptor molecule containing nucleotides and that the adaptor is the part that actually fits on the RNA template. Crick thus predicts the discovery of transfer RNA.

F. Jacob and E. L. Wollman demonstrate that the single linkage group of E. coli is circular and suggest that the different linkage groups found in different Hfr strains result from the insertion at different points of a factor in the circular linkage group that determines the rupture of the circle.

M. Meselson and F. W. Stahl use the density gradient equilibrium centrifugation technique to demonstrate the semiconservative distribution of density label during DNA replication in E. coli.

1958

Boris Leonidovich Pasternak awarded the Nobel Prize in Literature "for his important achievement both in contemporary lyrical poetry and in the field of the great Russian epic tradition".

Jack Kilby created the first integrated circuit

image Gigi wins Academy Award for best picture. Alan Jay Lerner and Frederick Loewe, fresh off the success of Broadway s My Fair Lady, wrote a score for this musical version of Colette s tale about a young girl being groomed to become a courtesan in Paris. The film made Oscar history by winning every award it was nominated for: nine for nine.

Severo Ochoa and Arthur Kornberg share a Nobel Prize in Medicine for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxiribonucleic acid.

J. Lejeune, M. Gautier, and R. Turpin show that Down syndrome is a chromosomal aberration involving trisomy of a small telocentric chromosome.

R. L. Sinsheimer demonstrates that bacteriophage phiX174 of E. coli contains a single-stranded DNA molecule.

1959

Salvatore Quasimodo awarded the Nobel Prize in Literature "for his lyrical poetry, which with classical fire expresses the tragic experience of life in our own times".

image On January 12, Berry Gordy, Jr., Founds Motown Records in Detroit.

image The US flag is modified to have forty-nine stars, reflecting the addition of one new state: Alaska.

COBOL is introduced

The Xerox 914 is the first office copier for sale

AGFA introduces the first fully automatic camera, the Optima.

Nikon F introduced.

Mary Leakey finds hominid skull belonging to Paranthropus boisei.

image Ben-Hur wins Academy Award for best picture. The production was wildly over budget, and some worried that Hollywood s early-1950s craze for biblical epics had already peaked. But the film, which is still famous for its chariot-race sequence, won 11 Oscars a record it held for 38 years, until Titanic also received 11.

ESP Quick Facts

ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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Timeline

The new, dynamic Timeline from the Electronic Scholarly Publishing Project gives users more control over the timeline display.

We seek your suggestions for timeline content, both for individual events and for entire subjects.

To submit a correction or a recommendation or to propose new Timeline content (or to volunteer as a Timeline Editor), click HERE.

The Electronic Scholarly Publishing Project needs help: with acquiring content, with writing, with editing, with graphic production, and with financial support.

CLICK HERE to see what ESP needs most.

ESP Picks from Around the Web (updated 06 MAR 2017 )