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About | Classical Genetics | Timelines | What's New | What's Hot

About | Classical Genetics | Timelines | What's New | What's Hot

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The Electronic Scholarly Publishing Project: Providing access to classic scientific papers and other scholarly materials, since 1993. More About:  ESP | OUR CONTENT | THIS WEBSITE | WHAT'S NEW | WHAT'S HOT

ESP Timelines

Comparative Timelines

The ESP Timeline (one of the site's most popular features) has been completely updated to allow the user to select (using the timeline controls above each column) different topics for the left and right sides of the display.

Select:

New Left Column

New Left Column

Dates

Decade

New Right Column

New Right Column

image The numerical equality of paternal and maternal chromosomes at fertilization was established by Theodor Boveri and Jean-Louis-Léon Guignard.

1890

image The numerical equality of paternal and maternal chromosomes at fertilization was established by Theodor Boveri and Jean-Louis-Léon Guignard.

(no entry for this year)

1891

(no entry for this year)

image Publication of August Weismann's book Das Keimplasma (The Germ Plasm) emphasized meiosis as an exact mechanism of chromosome distribution.

Joseph Whiteaves describes Anomalocaris, meaning "anomalous shrimp," from the Cambrian. The fossil that Whiteaves identifies as a shrimp will later prove to be part of a much larger animal.

1892

image Publication of August Weismann's book Das Keimplasma (The Germ Plasm) emphasized meiosis as an exact mechanism of chromosome distribution.

Entomologist E.B. Poulton studies caterpillars from the species Gastropacha quercifolia, noting how siblings look different depending on where they live and what they eat. His discovery will become known as phenotypic plasticity.

1893

(no entry for this year)

image Hans Driesch expounded the view that all nuclei of an organism were equipotential but varied in their activity in accordance with the differentiation of tissues.

image Karl Pearson published the first in a long series of contributions to the mathematical theory of evolution. Methods for analyzing statistical frequency distributions were developed in detail.

image William Bateson's Materials for the Study of Variation emphasized the importance of discontinuous variations, foreshadowing the rediscovery of Mendel's work.

Eugène Dubois publishes his monograph of Pithecanthropus erectus, or Java Man, a missing link between humans and apes.

French paleontologist Charles Brongniart describes a fossil dragonfly from the Carboniferous with a 2-foot (63-centimeter) wingspan. The find implies a higher oxygen content in the Earth's ancient atmosphere.

image The intricately carved mammoth ivory figurine known as the Lady (or Venus) of Brassempouy is discovered in France. At roughly 25,000 years old, it ranks among the earliest known depictions of a human face.

1894

image Hans Driesch expounded the view that all nuclei of an organism were equipotential but varied in their activity in accordance with the differentiation of tissues.

image Karl Pearson published the first in a long series of contributions to the mathematical theory of evolution. Methods for analyzing statistical frequency distributions were developed in detail.

image William Bateson's Materials for the Study of Variation emphasized the importance of discontinuous variations, foreshadowing the rediscovery of Mendel's work.

A team of paleontologists, including Samuel Williston, Elmer Riggs and Barnum Brown, successfully excavates a Triceratops fossil in Wyoming.

1895

(no entry for this year)

image E. B. Wilson publishes The Cell in Development and Heredity. This influential treatise (ultimately reprinted in several editions) distills the information compiled concerning cytology in the half-century since Schleiden and Schwann put forth the cell theory.

Dublin anatomist Daniel Cunningham concludes that Neanderthals represent an intermediate step between Pithecanthropus erectus and modern humans.

J. de Morgan describes nine pierced fossil urchins found in a Chalcolithic tomb at Toukh.

1896

image E. B. Wilson publishes The Cell in Development and Heredity. This influential treatise (ultimately reprinted in several editions) distills the information compiled concerning cytology in the half-century since Schleiden and Schwann put forth the cell theory.

image Gabriel Bertrand coined the term COENZYME to designate inorganic substances which were necessary to activate certain enzymes.

1897

(no entry for this year)

(no entry for this year)

1898

(no entry for this year)

image image L. Cuénot (France) working with animals, and Strasburger (Germany) working with plants, advance theory that sex is controlled within the germ cell, not by environment.

Richard Altmann renames "nuclein" as NUCLEIC ACID.

The First International Congress of Genetics held in London.

image William Bateson writes a paper on hybridisation and cross-breeding as a method of scientific investigation that anticipates Mendel's rediscovery.

1899

image image L. Cuénot (France) working with animals, and Strasburger (Germany) working with plants, advance theory that sex is controlled within the germ cell, not by environment.

Richard Altmann renames "nuclein" as NUCLEIC ACID.

The First International Congress of Genetics held in London.

image William Bateson writes a paper on hybridisation and cross-breeding as a method of scientific investigation that anticipates Mendel's rediscovery.

ESP Quick Facts

ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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Timeline

The new, dynamic Timeline from the Electronic Scholarly Publishing Project gives users more control over the timeline display.

We seek your suggestions for timeline content, both for individual events and for entire subjects.

To submit a correction or a recommendation or to propose new Timeline content (or to volunteer as a Timeline Editor), click HERE.

The Electronic Scholarly Publishing Project needs help: with acquiring content, with writing, with editing, with graphic production, and with financial support.

CLICK HERE to see what ESP needs most.

ESP Picks from Around the Web (updated 06 MAR 2017 )